Modeling stochastic gene expression in growing cells
نویسندگان
چکیده
منابع مشابه
Modeling stochastic gene expression in growing cells.
Gene expression is an inherently noisy process. Fluctuations arise at many points in the expression of a gene, as all the salient reactions such as transcription, translation, and mRNA degradation are stochastic processes. The fluctuations become important when the cellular copy numbers of the relevant molecules (mRNA or proteins) are low. For regulated genes, a computational complication arise...
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Gene networks arise due to the interaction of genes through their protein products. Modeling such networks is key to understanding life at the most basic level. One of the emerging challenges to the analysis of genetic networks is that the cellular environment in which these genetic circuits function is abuzz with noise. The main source of this noise is the randomness that characterizes the mot...
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ژورنال
عنوان ژورنال: Journal of Theoretical Biology
سال: 2014
ISSN: 0022-5193
DOI: 10.1016/j.jtbi.2014.01.017